Resveratrol Side Effects





Some people have reported Resveratrol side effects? Is there anything to be concerned about?

Resveratrol is a powerful anti-oxidant normally found in small amounts in red wine, Japanese knotweed (polygonum cuspidatum), the skin of red grapes, blueberries, bilberries, cranberries, raspberries, jackfruit, pomegranate, peanuts and cocoa.

It has been shown to control inflammation, proven effective at lowering sugar in the blood, is good for the heart and has also been shown to have many anti-cancer and anti-diabetic properties. It appears to have many health benefits but some people have reported some side effects and although no research has never shown it to be harmful research is still being conducted.

The most important thing you should be aware of is that the vast majority of people do not report any Resveratrol side effects.

Side effects tend to occur in individuals taking large amounts of Resveratrol or Resveratrol in combination with other substances (so Resveratrol may not be responsible).

These are the most commonly mentioned Resveratrol side effects

  • Tendinitis Pain – taking Resveratrol in high doses can cause pain in the tendons.Allied to this is joint ache in the hips, hands and feet
  • Achiles tendinitis – usually disappears if dosage is reduced
  • Insomnia which lasts for varying amounts of time but usually subsides after a week or so.
  • Diarrhoea and stomach cramps – probably connected to Emodin in some of the lower quality products that use Japanese knotweed as the Resveratrol source. You can avoid emodin if you only buy products that are 99% Pure Trans-Resveratrol]
  • Decreased appetite- which can make resveratrol useful for weight loss programmes
  • Colored urine – not particularly of concern,
  • Minor cold or flu like symptoms.
  • Increase in acne
  • Dizziness or a buzzed feeling similar to a caffeine rush (be aware that some resveratrol products are blended with caffeine).
  • An increase in blood pressure occasionally into the "high" range. This is unusual, since there is plenty of anecdotal evidence that Resveratrol tends to lower high blood pressure
  • An increased sensitivity to hot & cold temperatures.
  • Numbness in the extremities.
  • Heart Palpitations.
  • Swelling of the ankles or feet.
  • Small itchy skin eruptions that look like bug bites

Most people do not get these symptoms and there has been no studies that show that there are any toxic or harmful resveratrol side effects.



No-one has reported any resveratrol side effects from the product that we use (Jeunesse Reserve).

If you do find that you are suffering from side effects,‘What can you do?’

1.You have been taking resveratrol in small amounts (a few milligrams) every day for most of your life because it is in food but you probably don’t need to take more that 250-300 mg each day.

It is usually higher doses or when Resveratrol is mixed with other ingredients that the Resveratrol side effects occur.

Simply cut down the amount you are taking if you have any side effects or switch brands to one that has 99% Pure Trans-Resveratrol.

You can also cycle on and off the supplement so that you have a break from it, e.g. take it for a couple of weeks then take a week off and repeat.

2. Talk to your doctor before taking resveratrol, especially if you are taking any medications.

For example, resveratrol supplements have the potential to interact with blood thinners like warfarin (Coumadin), and anti-inflammatory medications like aspirin and ibuprofen, which may increase the risk of bleeding. Because of its effect on estrogen metabolism there is the potential for it to decrease the effectiveness of birth control pills but no studies have been done to confirm this. It should also not be used by pregnant women or young children simply because not enough research has been done on its effect on the young.

My wife and I, and many of our friends use Jeunesse Reserve gel and no-one has reported any side effect from using it.

All feedback has been positive and it is the one that we recommend but there are others that are probably as good.  Do your research.

If you would like to learn more about resveratrol please click here


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